Fig. 7
From: Tryptophan-sorbitol based carbon quantum dots for theranostics against hepatocellular carcinoma
Induction of autophagy by photoexcited TC-WS-CQDs in Huh7 cells. A Detection of autophagosomes by TEM. Arrows indicate autophagosomes. B Western-blot analysis of LC3 conversion, expression of Beclin-1 and p62. C Fluorescence images of LC3 puncta expressing mcherry-GFP-LC3. Autophagosomes and autolysosomes were observed in Huh7 cells. The data in C are mean ± SD (n = 3, statistical significance was analyzed via Mann–Whitney test, *p < 0.05). D Western-blot analysis of expression of p53 and phosphorylation AMPK. CQDs + I470nm: TC-WS-CQDs with 470 nm irradiation, I470nm: 470 nm irradiation without TC-WS-CQDs, CQDs: TC-WS-CQDs, Control: no TC-WS-CQDs and irradiation