Fig. 13

a Schematic diagram of the anticancer mechanism of multifunctional BP@Cu@PEG-RGD hybrid nanomaterials in vivo [133]. b Relative tumor volume after different treatments on day 14 [133]. c Inhibitory rates of B16F10 tumors at day 14 post-treatment [133]. d MIP PET images of B16F10 tumor-bearing mice after 2 weeks of treatment with saline or BP@Cu_0.4@PEG-RGD, respectively. PET images were taken at 30 and 40 h after intravenous injection of saline or BP@⁶⁴Cu@PEG-RGD. The white circles denote the tumor sites. Reproduced with permission. [133]