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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: The effects of extracellular vesicles derived from Krüppel-Like Factor 2 overexpressing endothelial cells on the regulation of cardiac inflammation in the dilated cardiomyopathy

Fig. 3

KLF2-EVs reduced the expression of inflammatory factors and decreased Ly6Chigh Mo/Mø ratios in heart tissue. A RT–qPCR analyses of IL-1β、TNF-α 、IL-10 and TGF-β expression. B Representative flow cytometry plots showing CD11b + Ly6Chigh cells in the heart. C Quantification of CD11b + Ly6Chigh cells (Ly6Chigh Mo/Mø) within the heart tissue. D Representative flow cytometry plots showing CD11b + Ly6Chigh cells in peripheral blood. E Quantification of CD11b + Ly6Chigh cells (Ly6Chigh Mo/Mø) within blood. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns = not significant

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Journal of Nanobiotechnology

ISSN: 1477-3155

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