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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Biomimetic nanoprobe-augmented triple therapy with photothermal, sonodynamic and checkpoint blockade inhibits tumor growth and metastasis

Fig. 7

In vivo activation of immune responses triggered by PTT/SDT. A The DC maturation levels induced by CHINPs-based PTT/STT on 4T1 tumor-bearing mice (gated on CD11c+ DC cells) analyzed by flow cytometry and B the corresponding quantitative analysis. C The CD8+ T cells (CD3+CD8+) analyzed by flow cytometry and D the corresponding quantitative analysis. E The Treg cells (CD3+CD4+Foxp3+) analyzed by flow cytometry and F the corresponding quantitative analysis. G–I Cytokine levels in sera from mice isolated at 7d post different treatments. Data shown are mean ± SD (n = 3). Statistical differences determined by one-way ANOVA; *p < 0.05, **p < 0.01, ***p < 0.0001, ****p < 0.0001

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