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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Thermo/pH dual-responsive micelles based on the host–guest interaction between benzimidazole-terminated graft copolymer and β-cyclodextrin-functionalized star block copolymer for smart drug delivery

Fig. 7

Fluorescence microscopic images of DAPI stained MCF-7 cells following 48 h of exposure to untreated cells (control) (a), free DOX (IC50) (b), free DOX (50 μg/mL) (c), DOX-loaded micelles (IC50) (d), and DOX-loaded micelles (50 μg/mL) (e). The percentages of apoptotic cell death in MCF-7 cells after being exposed to free DOX, and DOX-loaded micelles (f). As displayed in the diagram, DOX-loaded polymeric micelles yield highly considerable apoptosis (p < 0.01) in comparison to free DOX. Each value represents the mean value ± standard deviation (n = 3, *p < 0.05, ** p < 0.01, *** p < 0.001, ****p < 0.0001). Images were taken at magnification (×200) and (×400)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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