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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Facile synthesis of near-infrared responsive on-demand oxygen releasing nanoplatform for precise MRI-guided theranostics of hypoxia-induced tumor chemoresistance and metastasis in triple negative breast cancer

Fig. 4

In vivo antitumor therapeutic efficacy for NIR-triggered O2-PPSiI. A–C The relative changes of volume (â–³Volume) in each groups before and after the treatments, together with the â–³Volume and weight of tumors of each groups at the 21 days after the treatment. Significant difference between the Saline and treatment groups is indicated at P < 0.05 (*) or P < 0.001 (**) level. D The representative images for tumor volume derived from 3D-CUBE T2WI in each group at the 21 days after the treatment. E IVIM-DWI derived D mapping of tumor in each group before and after the treatment. F, G The corresponding HE and TUNEL staining images at the 21 days after the treatment. (G1:Saline; G2:Laser; G3:PTX; G4: O2-PPSiI; G5:PPSiI + Laser; G6:O2-PSiI + Laser; G7: O2-PPSiI + Laser)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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