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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Facile synthesis of near-infrared responsive on-demand oxygen releasing nanoplatform for precise MRI-guided theranostics of hypoxia-induced tumor chemoresistance and metastasis in triple negative breast cancer

Fig. 5

Anti-migration and anti-invasion effects of NIR-triggered O2-PPSiI. A Wound healing assay of each group on MDA-MB-231 cells. B Transwell assay of each groups on MDA-MB-231 cells. C Real-time monitoring the cell invasion of each group on MDA-MB-231 cells. D The immunohistochemistry for the epithelial-specific marker E-cadherin and the mesenchymal-specific markers vimentin and Snail-Slug in each group at 21 days after treatment. E The relative integrated optical density (IOD) of E-cadherin, vimentin and Snail-Slug in each group at 21 days after treatment, and significant difference between the Saline and treatment groups is indicated at P < 0.05 (*) or P < 0.001 (**) level

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