Fig. 5

In vivo antitumor effect of ACaT on SKOV3 ovarian tumor-bearing mice. A The timeline of animal experiment. B In vivo bioluminescent images of mice after different treatments (n = 5). C Individual fluorescence intensity of mice treated with PBS, NaALN, THZ1 and ACaT calculated from the in vivo bioluminescent images. D Average fluorescence intensity of mice treated with PBS, NaALN, THZ1 and ACaT (means ± SD, n = 5). E Tumor weight and representative images of tumor tissues harvested on day 35 (means ± SD, n = 3). F Ascites weight and representative images of ascites harvested on day 35 (means ± SD, n = 3). G Kaplan–Meier survival curves of mice in the different treatment groups. H H&E and TUNEL staining images of tumor tissues for each group after 35 days treatment. Scale bar: 100 μm