Fig. 9
The PGE2 matrix promoted recovery of hindlimb function. A Representative H&E-stained images of muscle tissue with different treatment on day 14. n = 5. Scale bar, 100 μm. B Representative images of anti-CD45 immunohistochemical staining in injured muscles on day 14. n = 5. Scale bar, 100 μm. C Masson’s trichrome staining of muscle sections on day 28. n = 5. Scale bar, 100 μm. D Schematic diagram of the PGE2 release matrix for muscle regeneration. Preparation of the PGE2 matrix to extend the release of PGE2 with therapeutic potential to treat hindlimb ischemia by promoting neovascularization and MyoD1-mediated regeneration of skeletal muscle