Fig. 5

In vivo FERT of HepG2 tumors. a Illustration of the treatment procedure. Tumor-bearing mice were treated as indicated. b Representative photographic images of mice at various time points. c Photographic images of tumors harvested from mice after termination of the monitoring period. d–g Individual tumor growth curves of the mice in the PBS (d), FePt (e), X-ray (f) groups, and FERT group (g). h Relative tumor volume curves for the various treatment groups. The statistical differences were derived from the comparison between the corresponding groups (PBS, FePt, X-ray) and the FERT group, respectively. (****P < 0.0001, **P < 0.01). i Survival curves of the various groups. The statistical differences were derived from the comparison between the corresponding groups (PBS, FePt, X-ray) and the FERT group, respectively. (**P < 0.01, *P < 0.05). j Body weights as functions of time of mice in the various treatment groups. k Tumor weights of mice in the various groups. l Images of tumor slices stained with H&E collected from various groups of mice (scale bar: 100 μm)