Fig. 2
From: Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia
The characterization of ITIC-Th NPs. A Optical image of the ITIC-Th NPs water solution in a cuvette. B The TEM image of ITIC-Th NPs in water solution. Scale bar = 100 nm. C The DLS profiles of ITIC-Th NPs in water (10 μg/mL). The average diameters of ITIC-Th NPs were approximately 60 nm, consistent with the TEM result. D The corresponding energy-dispersive spectroscopy (EDS) results of ITIC-Th NPs (The corresponding elements were marked in different colors in the image). E UV absorbance spectrum of ITIC-Th and ITIC-Th NPs (20 μg/mL) solution. F The fluorescence emission spectrum of ITIC-Th and ITIC-Th NPs under emission of 660 nm. G The average diameter of ITIC-Th NPs in corresponding solutions (water, PBS, DMEM, and FBS) after 2 weeks. H Photothermal profiles of ITIC-Th NPs in PBS under different power density irradiation (660 nm, 0.4, 0.6,0.8,1.0, and 1.2 W/cm2). I Photothermal profiles of ITIC-Th NPs in PBS with different concentrations (6.25, 12.5, 25.0, and 50.0 μg/mL) under laser irradiation (660 nm, 1 W/cm2). J The heating curve of the ITIC-Th NPs in PBS during 5 cycles of on-and-off laser irradiation (660 nm, 1 W/cm2). K Fluorescence spectra of ITIC-Th (20 μg/mL) mixed with SOSG (10–5 mol/L) upon laser irradiation (660 nm, 1 W/cm2) with various duration. L Fluorescence intensity was measured at different time intervals. M Absorption spectra of ITIC-Th (20 μg/mL) mixed with DPBF (6 × 10−5 mol/L) under laser irradiation (660 nm, 1 W/cm2) with various durations