Fig. 2

Assessment of the thermal stability of RNase A@PbS/ZnS QDs. A Schematic illustration of the in vitro study protocol. B The PL spectra of RNase A@PbS/ZnS QDs solution at different temperatures. C Schematic illustration of the in vivo study protocol on living mice. D Thermal images of mice under irradiation of 808 nm or 1064 nm after systemic administration of RNase A@PbS/ZnS QDs. E Rising temperature at the irradiation region or the extremities under irradiation of 808 nm or 1064 nm. F Maximum temperature as a function of laser irradiation time after systemic administration of RNase A@PbS/ZnS QDs. G Minimum temperature as a function of laser irradiation time after systemic administration of RNase A@PbS/ZnS QDs. * indicated P < 0.05