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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Exposure to two-dimensional ultrathin Ti3C2 (MXene) nanosheets during early pregnancy impairs neurodevelopment of offspring in mice

Fig. 4

Changes in the neurobehavior and brain morphology of offspring after maternal exposure to Ti3C2 nanosheets. a The escape latency to the hidden platform during the directional navigation test period. b The total swim distance per day during the directional navigation test. c The average swim speed per day during the directional navigation test. d The number of platform crossings during the spatial probe trial. e Representative images of offspring in the spatial probe trial. f The percentage of the number of entries into the open arm. g The percentage of the time stays in the open arm. h Representative photomicrographs of morphological changes in the hippocampus and cortex (scale bars = 50 μm and 20 μm). Each experiment was repeated at least three times. Data in a–g are shown as means ± SD (n = 4 mice per group). *p < 0.05, **p < 0.01 vs. Control group

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