Fig. 12
Advanced MSNs for bioimaging application. A High-resolution TEM images of HMSNs@Au nanostars. B Ultrasonographic images of water, HMSNs@Au nanostars@ perfluorohexane (HAP), and HAP@mPEG (HAPP) with different concentrations under contrast mode. C CT images of (1) HAPP and (2) Omnipaque with different concentrations of the radiodense element (Au or I). D PA images of HAPP with different Au concentrations. Reproduced with permission from Ref. [374] Copyright 2017, American Chemical Society. E T2 phantom images of AuNRs-MMSNEs at different Fe concentrations. F Relaxation rate 1/T2 of AuNRs-MMSNEs as a function of Fe concentration. G In-vivo MRI of a mouse before and after intratumor injection of Au NRs-MMSNEs. H Photographs of AuNRs-MMSNEs dispersed in water before (left) and after (right) an external magnetic attraction. I Infrared thermal imaging under the photothermal heating by 808 nm laser irradiation for different periods in AuNRs-MMSNEs-injected tumor under 2 W cm−2 irradiation. Reproduced with permission from Ref. [142] Copyright 2012, Elsevier