Fig. 2

Effects of Cur@Hb nanoparticles on SMMC7721 cell proliferation, cell cycle, and apoptosis. A Cytotoxic effects of Hb, Cur and Cur@Hb on SMMC7721 cells. B Quantitative analysis of fluorescence intensity. C, D Effects of Hb, Cur and Cur@Hb nanoparticles on cell proliferation under normoxia or hypoxia. E, F Effects of Hb, Cur and Cur@Hb nanoparticles on cell apoptosis under normoxia or hypoxic condition, with or without 4 Gy irradiation. Data are representative of three independent experiments and expressed as mean ± SD (n = 3, technical replicates), one-way ANOVA followed by Bonferroni post-test, *p < 0.05, **p < 0.01, and ***p < 0.001