Fig. 5

Effects of Cur@Hb nanoparticles on the DNA damage of SMMC7721 cells induced by 4 Gy X-ray. A-D: Cur@Hb nanoparticles aggravated DNA damage during normoxia (A, C) and hypoxia (B, D); E, F Pictures of single cell gel electrophoresis. G, H Histogram of quantitative analysis of comet assay under normoxia (E) or hypoxia (H). Data are representative of three independent experiments and expressed as mean ± SD, one-way ANOVA followed by Bonferroni post-test, *p < 0.05, **p < 0.01, and ***p < 0.001