Fig. 4
From: A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
CeNP-PEG inhibited the proinflammatory profile of macrophages. A Schematic diagram of the experimental setup to evaluate the effect of CeNP-PEG decreased the proinflammatory profile of BMDMs. B CD86 expression levels in BMDMs treated with different concentrations of CeNP-PEG. C Western blotting analysis of proinflammatory phenotype biomarkers including iNOS, IL-1β, IL-6, TNF-α, and INF-γ in BMDMs. D The mRNA levels of TNF-α, IL-6, IL-1β and IFN-γ in BMDMs after treatment with complete medium, 100 ng/mL LPS + 20 ng/mL IFN-γ in the presence or absence of CeNP-PEG (0.5 or 1.0 μg/mL). E The concentrations of TNF-α, IL-6, IL-1β, and IFN-γ in BMDMs culture media after the above treatments. The data are presented as the mean ± SD (n = 3). One-way ANOVA was used for statistical analysis. MFI: mean fluorescence intensity