Fig. 5
From: A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
CeNP-PEG exhibited a therapeutic effects on a DSS-induced colitis model. A Schematic diagram of colitis mouse model establishment and CeNP-PEG treatment strategies. B Normalized mouse body weights as a function of time during the experiment (n = 6). C Disease activity index (DAI) score of colitis model mice during the experiment (n = 6). D Photographs of the excised colons from the colitis models at day 9 after treatment. E Measurements of colon lengths after different treatments (n = 6). F Intestinal permeability was examined by measuring the concentration of FITC-dextran in the serum (n = 4). G Representative H&E-stained colonic sections at day 9 after treatment. Scale bar = 50 μm. H The histology score of colitis in the models after different treatments (n = 3). The data are presented as the mean ± SD. One-way ANOVA was used for statistical analysis