Skip to main content
Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation

Fig. 3

BHB inhibited ASC oligomerization, speck formation, and pyroptosis. A Representative image of Cross-linked cytosolic pellets of ASC oligomerization by western blot. B Representative western blot image of GSDMD in cell lysates. GSDMD NT: Gasdermin-D N-terminal. GSDMD FL: Gasdermin-D full length. C Quantification analysis of ASC speck. D Representative images of ASC speck formation by immunofluorescence. Scale bar: 200 μm (panel), 20 μm (inset). White arrows indicate ASC specks

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us