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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation

Fig. 6

BHB inhibits that function of osteoclast. A Representative co-staining (MMP9 and TRAF6) immunofluorescence image of osteoclast. Scale bar: 200 μm. B Representative image of CTSK, MMP9, TRAP after invention with BHB by western blot. C The gene expression of CTSK, MMP9, and TRAP. n = 3. D Quantification of CTSK, MMP9, and TRAP. n = 3. E Representative Phalloidin labeling F-actin image of osteoclasts. Scale bar: 200 μm. Results are mean ± SEM. *p < .05

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