Fig. 8

The inhibitory effects of BHB on osteoclast rely on HDAC suppression. A Representative TRAP staining of osteoclast. Scale bar: 200 μm. B Quantification of multi-nucleated TRAP-positive cells. C Representative image of TRAF6, NFATc-1, c-Fos, CTSK, MMP9, and TRAP after invention with BHB by western blot. D Quantification of TRAF6, NFATc-1, c-Fos, CTSK, MMP9, and TRAP. n = 3. Results are mean ± SEM. ^#p < .001