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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Cur@SF NPs alleviate Friedreich’s ataxia in a mouse model through synergistic iron chelation and antioxidation

Fig. 7

Cur@SF NPs significantly improved myocardial function. A, B H&E staining to evaluate the improvement of cardiomyocyte hypertrophy by counting the diameter of cardiomyocytes. C TEM results to observe the mitochondrial morphology and internal ultrastructure. D Detection of aconitase activity (purple) and protein levels of mitochondrial proteins. mAco2: mitochondrial aconitase (Aco2) activity. E, F The activities of mitochondrial complexes I and II. G ATP content. H A schematic diagram depicting Cur@SF NPs alleviating FRDA through synergistic iron chelation and antioxidation. (*p < 0.05; ****p < 0.0001, YG8R + NPs vs. YG8R, n = 5/group)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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