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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Curcumin primed ADMSCs derived small extracellular vesicle exert enhanced protective effects on osteoarthritis by inhibiting oxidative stress and chondrocyte apoptosis

Fig. 6

sEV-CUR exhibit an enhanced protective function in ACLT-induced OA mice. a Representative images of H&E, Safranin O-Fast Green (S–O) staining, and Toluidine blue staining of articular cartilage in each group, scale bar: 100 μm; b statistic data of Mankin scores in each group (n = 6); c representative image of H&E staining of synovium in each group, scale bar: 100 μm; d statistical analysis of synovitis score in each group (n = 6); e representative image of immunohistochemistry staining for extracellular matrix anabolism biomarker aggrecan and collagen II in each group, scale bar: 100 μm; f, g quantitative analysis of immunohistochemical staining of aggrecan and collagen II (n = 6). NS, not significant, *P < 0.05, **P < 0.01, ***P < 0.001

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