Fig. 7From: Curcumin primed ADMSCs derived small extracellular vesicle exert enhanced protective effects on osteoarthritis by inhibiting oxidative stress and chondrocyte apoptosis sEV-CUR exert an improved anti-oxidative and anti-apoptosis ability in vivo. a, b Representative images and quantitative analysis of immunohistochemistry staining for a classical oxidative stress biomarker 8-OHdG in each group (n = 6), scale bar: 50 μm; c, d representative images and quantitative analysis of immunohistochemistry staining for a classical apoptosis biomarker cleaved caspase3 in each group (n = 6), scale bar: 50 μm; e, f representative images and quantitative analysis of TUNEL staining analysis to detect chondrocyte apoptosis (Red) in vivo in each group (n = 6), scale bar, 100 μm. NS, not significant, *P < 0.05, ***P < 0.001Back to article page