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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Curcumin primed ADMSCs derived small extracellular vesicle exert enhanced protective effects on osteoarthritis by inhibiting oxidative stress and chondrocyte apoptosis

Fig. 7

sEV-CUR exert an improved anti-oxidative and anti-apoptosis ability in vivo. a, b Representative images and quantitative analysis of immunohistochemistry staining for a classical oxidative stress biomarker 8-OHdG in each group (n = 6), scale bar: 50 μm; c, d representative images and quantitative analysis of immunohistochemistry staining for a classical apoptosis biomarker cleaved caspase3 in each group (n = 6), scale bar: 50 μm; e, f representative images and quantitative analysis of TUNEL staining analysis to detect chondrocyte apoptosis (Red) in vivo in each group (n = 6), scale bar, 100 μm. NS, not significant, *P < 0.05, ***P < 0.001

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