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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

Fig. 4

DOX conjugated bovine serum albumin (BSA) NPs can target proinflammatory neutrophils and induce their apoptosis in situ. DOX is conjugated to NPs through a pH-labile hydrazone bond, which can be cleaved by the low PH environment in activated neutrophils to release DOX and induce neutrophil apoptosis. Reprinted with permission [90]. Distributed under a Creative Commons Attribution NonCommercial License 4.0

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