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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy

Fig. 7

MSC-BMP2-Exos expedited cortical bone regeneration. a Holes with diameters of 1 mm were created at mid-diaphysis of femora. Micro-CT was performed on day 15 and day 30. b, c Representative reconstructed 3D images of cortical bone at injured sites. The injured areas are highlighted by yellow color. Scale bars: 500 μm. d Quantitative analysis of BV/TV and Cr.Th for cortical bones at injured sites, n = 5. *p < 0.05, **p < 0.01, ***p < 0.001

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