Fig. 2

The effect of dose on tumor delivery of PEG-liposomes in 4T1 tumor-bearing mice. The dynamic biodistribution of PEG-Lipo via whole-mouse imaging at doses of a 12 mg/kg, b 50 mg/kg and c 80 mg/kg equivalent phospholipids. The ex vivo distribution of PEG-Lipo at doses of d 12 mg/kg and e 50 mg/kg and 80 mg/kg equivalent phospholipids. At a dose of 12 mg/kg, the half-quantitative analysis of the fluorescence intensity in tumor and liver f in vivo and g ex vivo. h The ex vivo fluorescence intensity in the tumor and liver at the end of the experiment. Data represent the mean ± SD (n = 3)