Fig. 4

In vivo antitumor efficacy and biodistribution in 4T1 tumor-bearing mice. a During the experiment, the tumor growth curve of mice in the four groups was delineated. ^**P < 0.01 vs. Normal saline; ^&P < 0.05 vs. no enhancer. b The weight change of mice with time in each group. c At 24 h after administration, the distribution of the + enhancer group and the no enhancer group in related tissues and organs of mice was imaged. d At 24 h after administration, the relative fluorescence intensity and ratio of the + enhancer group and the no enhancer group in the tumor and liver were calculated. Data represent the mean ± SD (n = 6)