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Table 3 Previously described and characterized properties of G2-S16 dendrimer

From: Safety and efficacy of G2-S16 dendrimer as microbicide in healthy human vaginal tissue explants

G2–S16 phisicochemical properties

General characteristic

 Molecular formula

C112H244N8Na16O48S16Si13

 Molecular weigh

3717.15 g/mol

 Structure

Anionic carbosilane dendrimer

 Generation

G2

 Core

Silica

 Functional groups

SO 3

 Number of peripheral groups

16

Structural parameters

 R [nm]

1.767 ± 0.103

 Rg [nm]

0.932 ± 0.020

 SASA [nm2]

33.63 ± 1.45

 SESA [nm2]

24.76 ± 0.33

 SEV [nm3]

3.330 ± 0.073

 SPHER

0.938 ± 0.024

Aqueous solutions parameters

 Z potential

 − 74.0 mV

 Diffusion coefficients (D, 10−11 m2/s)

4.99

 Hydrodynamic radii (rH, nm)

4.29

  1. R Molecular radius, Rg radius of gyration, SASA solvent accessible surface area, SESA solvent-excluded surface area, SEV solvent-excluded volume, SPHER sphericity