Fig. 7
From: Bacteria-driven hypoxia targeting delivery of chemotherapeutic drug proving outcome of breast cancer
Micro-PET/CT imaging and immunohistochemical analysis of tumor tissues after various treatments. A The images of 18F-FDG PET/CT scanning in mice on the 14th day after various treatments. B SUVmax and SUVmean values for various groups. C Representative micrographs of tumor tissue stained by TUNEL and immunohistochemistry to detect cleaved HIF-1α and SPARC in tumors. Scale bar, 50 μm. D The positive expression rates of TUNEL, HIF-1α and SPARC in tumor. Results are expressed as mean ± SD (n = 3). Asterisks indicate significant differences (ns: no statistical significance, *P < 0.05, ***P < 0.001, ****P < 0.0001)