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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Hydrogel supplemented with human platelet lysate enhances multi-lineage differentiation of mesenchymal stem cells

Fig. 4

The effect of HPL on the cell migration and angiogenesis of SHED. A Proteins related to cell migration and angiogenesis were constructed as a network of interactions, including APOB, APOD, MIF, CD44, PF4, APOE and FERMT3; B The cell migration of HUVEC in the co-culture system was observed; C The relative cell migration rate was calculated in the co-culture system; D The angiogenic differentiation of HUVEC was analyzed in a co-culture system; E Angiogenesis were performed statistically to analyze the tube number of per field in vitro; F The total length of the tube (μm) was statistically analyzed; G The branch number was statistically analyzed; Control group: HUVEC; SHED group: SHED co-culture with HUVEC; SHED + HPL group: SHED cultivated at HPL co-culture with HUVEC; One-way ANOVA was used for statistical significance. The data was shown in mean ± SEM. *: compare to control group, p < 0.05; #: compare to SHED group, p < 0.05

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