Fig. 6
a Schematic illustration of OFCCF-based Ca2+ release and production 1O2 activation of MPTP opening inhibits tumor growth. b The biodistribution of Fe in main tissues and tumor (c) and feces in different times after intravenously injecting with OFCCF into 4T1-tumor-bearing. Data were represented as mean ± SD (n = 3). d The biodistribution of Ca in tumor after various treatments at 12 h intravenously injecting into 4T1-tumor-bearing. Data were represented as mean ± SD (n = 3). e Apaf-1 level of tumor supernatant after various treatments. P values were calculated by one-way analysis (*p < 0.05, **p < 0.01, ***p < 0.001). Data were represented as mean ± SD (n = 3). f Western blot analysis Cyt c, Bcl-2 and Caspase 3 expression of tumor. g HIF-1α and DCFH-DA staining of tumor collected from mice after various treatments