Fig. 4

In vitro studies A IC50 analysis of PTC-M and PC-M, B Cellular uptake and intracellular distribution determined by fluorescence microscopy (scale bar = 200 µm), C Flow cytometry analysis and D Mean fluorescence intensity quantification of cellular uptake. E Cellular uptake of PTC-M determined by ICP-MS. Data is shown as mean ± SEM (n = 3 replicates). Statistics were performed by a one-way ANOVA (*P < 0.05, **P < 0.01, *** P < 0.001, and **** P < 0.0001)