Fig. 9

Effects of PTC-M on apoptosis and MAPK pathway in IRI mice kidneys. A Comparison of protein expression level for proteins related to apoptosis determined by immunoblotting from the kidney of sham, IRI, and IRI + PTC-M mice. B Protein expression of the total ERK, phosphorylated ERK (p-ERK), total JNK, phosphorylated JNK (p-JNK), P38 and phosphorylated P38 (pP38) was assessed in the kidney of sham, IRI, and IRI + PTC-M mice. β-actin was used as the endogenous control. C Representative images of TUNEL staining in the kidney of sham, IRI and IRI + PTC-M mice. Scale bars, 25 μm. Data are shown as mean ± SEM. *P < 0.05 vs. sham mice; ^#P < 0.05 vs. IRI mice. TUNEL Terminal deoxynucleotidyl transferase dUDP nick-end labeling