Fig. 5

A The in vivo biodistribution of the DiR-loaded BFE@BSA NPs (n = 3, different mice for each time point). The quantitative analysis of fluorescence intensity of tumor (B) and relative fluorescent ratio of tumor/liver (C). D Schematic diagram of 4T1 tumor treatment. The 4T1 tumor growth curve (E), body weight of mice (F) and tumor weight (G) after different treatments (n = 5). H The photograph of tumors after different treatments. I H&E and masson’s trichrome staining of the lung sections from the mice after different treatments. Statistical p values: *p < 0.05, **p < 0.01, ***p < 0.001