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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer

Fig. 1

Preparation and characterization of ZnPc-EVs. Representative a Cryo-TEM micrograph, b size distribution by NTA, c western blot analysis of EV markers and d M1- polarized RAW 264.7 cells were investigated for CD68 expression (left panel) and M2-polarized RAW 264.7 cells were investigated for CD163 expression (right panel) by flow cytometry after incubation with the ZnPc-EVs, IFN-y and LPS, or IL-4 for 24h. e Viability of MC38 cells after incubation for 24, 48 or 72 h various concentration of the ZnPc-EVs. (scale bars are 10 nm.****P < 0.0001; mean ± SEM; n = 3)

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