Fig. 1

Characterizations and microenvironmental reactivity of DHA@MIL-101 NRs. A, B SEM and TEM images of MIL-101 NRs. C SEM images of DHA@MIL-101 NRs. D Powder XRD diffraction patterns of as-prepared MIL-101 NRs and DHA@MIL-101 NRs. E FTIR spectra of MIL-101 NRs, DHA and DHA@MIL-101 NRs. F Zeta potentials of MIL-101 NRs and DHA@MIL-101 NRs. G, H Schematic illustration, photos and morphology of DHA@MIL-101 NRs in response to pH (in PBS solutions with different conditions): G pH 7.4, treatment time is 12 h and 24 h, H pH 7.4, treatment time is 12 h and 24 h. I DHA molecules release profiles at the water, pH 7.4 and 5.2 from DHA@MIL-101 NRs. J iron ions release profiles at the water, pH 7.4 and 5.2 from DHA@MIL-101 NRs. K ESR analysis of ·OH production of DHA@MIL-101 NRs at different systems by using DMPO as the spin-trapping agent