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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: A novel nanobody-heavy chain antibody against Angiopoietin-like protein 3 reduces plasma lipids and relieves nonalcoholic fatty liver disease

Fig. 1

Schematic presentation of the whole experiment. The whole experimental procedure includes immunization with ANGPTL3, B-cells separation, VHH library construction, phage-display to select ANGPTL3-specific VHH, sanger sequencing, VHH and VHH-Fc fusion proteins expression, affinity determination, in vitro LPL assay and pharmacodynamic evaluation in hypercholesterolemic and NAFLD mice model

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Journal of Nanobiotechnology

ISSN: 1477-3155

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