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Table 2 In vivo NO production assessment

From: Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ

Group

Name

Treatment*

1

Control

Saline

2

LPS

LPS

3

PCM-MSN

PCM-MSN + LPS

4

MSN@LA

MSN@LA + LPS

5

PCM-MSN@LA

PCM-MSN@LA + LPS

6

PCM-MSN@LA + LIFU

PCM-MSN@LA + LPS, with LIFU irradiation

  1. *PCM-MSN, MSN@LA and PCM-MSN@LA were all administrated at a dosage of 1 mg kg−1 for 2 min before LPS injection