Table 1 Comparison of the proposed strategy with other reported methods
Method | Analyte | Time | Detection range | LOD (M) | Ref. |
|---|---|---|---|---|---|
Electrochemistry | miRNA-155 | 3 h | 1 × 10− 16–1 × 10− 8 M | 3.96 × 10− 17 | [4] |
Fluorescence | miRNA-21 | 70 min | 1 × 10− 14–1 × 10− 9 M | 8.1 × 10− 15 | [5] |
Fluorescence | E542K-ds-ctDNA | 250 min | 1 × 10− 12–1 × 10− 10 M | 3.161 × 10− 13 | [6] |
SERS | miRNA-21 | 60 min | 3.3 × 10− 16–3.3 × 10− 12 M | 4.2 × 10− 17 | [7] |
SERS | BRAF V600E | 5 min | 1 × 10− 17–1 × 10− 10 M | 3 × 10− 17 | [8] |
SERS | PIK3CA E542K | 13 min | 1 × 10− 17–1 × 10− 10 M | 1.26 × 10− 18 | This work |
TP53 | 2.04 × 10− 18 |