Fig. 6
From: Biomimetic nanobubbles for triple-negative breast cancer targeted ultrasound molecular imaging
In vivo effect of NBCCM and NBctrl on tumor enhancement by contrast-mode imaging. a Representative ultrasonographic images of SK-BR3 and MDA-MB-231 subcutaneous tumors before and after injection of NBCCM or NBctrl. The first and second columns show the B-mode and contrast-mode images of tumors before NB injection, respectively. The third to fifth columns show the non-linear signal at different time points after NB administration. Scale bar is 2 mm; b mean time intensity curves of both SK-BR3 and MDA-MB-231 tumors after NB injection; c comparison of NB kinetic parameters. Data are shown as Mean ± SEM; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; (n = 5)