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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Lipid-coated albumin-paclitaxel nanoparticles loaded with sorcin-siRNA reverse cancer chemoresistance via restoring intracellular calcium ion homeostasis

Fig. 2

Calcium-related gene expression and calcium ion concentration in chemoresistant A2780/PTX and A549/PTX cells and sensitive counterparts A2780 and A549 cells. a Half-maximal inhibitory concentration (IC50) was measured in A2780/PTX and A549/PTX and their sensitive counterparts. b–c Calcium ion concentration was determined in A2780/PTX and A549/PTX and their sensitive counterparts by flow cytometry. d–e The expression of SRI mRNA was higher in A2780/PTX and A549/PTX compared with their sensitive counterparts determined by qRT-PCR. f–g The expression of SRI protein was detected in A2780/PTX and A549/PTX and their sensitive counterparts by Western blot. PTX, paclitaxel; SRI, sorcin. **P < 0.01

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