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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Photoluminescent carbon dots (PCDs) from sour apple: a biocompatible nanomaterial for preventing UHMWPE wear-particle induced osteolysis via modulating Chemerin/ChemR23 and SIRT1 signaling pathway and its bioimaging application

Fig. 10

Inhibitory potential of PCDs in UHMWPE-induced osteolysis in mouse calvarial model. a Showing the representative micro-CT 3D image of PCD-treated calvaria. The red colour arrow indicates the bone loss in mouse calvaria. Graphs illustrating the (b) bone volume/total volume (BV/TV) and (c) total porosity of experimental group. Data are represented as mean ± SD; *P < 0.05 compared with sham control and #P < 0.05 compared with the UHMWPE group

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