Fig. 4
From: Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression
Intraperitoneal injection of arctiin ameliorated DMM-induced subchondral bone sclerosis in seven-week-old C57BL/6J male mice. A, B 2D reconstructed coronal and sagittal model of the mice knee joints. C 3D reconstructed model and the formation of osteocytes of the medial tibial plateau. D–F The effects of arctiin treatment on the values of bone volume ratio (BV/TV, %), trabecular thickness (Tb.Th, mm), and trabecular separation (Tb.Sp., mm−1) (n = 6). Values represent mean ± SD. Statistically significant differences are indicated by * where p < 0.05, ** where p < 0.01, *** where p < 0.001 and **** where p < 0.0001 between the indicated groups