Fig. 8

In vivo antitumour effects of MB@OVA/PPY NPs using a 4T1 subcutaneous tumour-bearing mouse model. A Infrared thermal images of mice at various time points during treatment under different conditions with 808 nm laser irradiation. B Corresponding temperature change curves of the breast tumour sites of the mice in different treatment groups upon laser irradiation. C Tumour volume change curves and D the body weight changes of the mice in the different treatment groups. Data are expressed as the means ± SD (n = 4) (***p < 0.001, ****p < 0.0001 by t test). E H&E-stained images of the major organs in the different treatment groups. Scale bar: 100 µm