Fig. 5

Interaction between Av–Au NCs and the DNA strands modified with biotin at both ends was confirmed with high-resolution transmission electron microscopy (HRTEM). HRTEM images with different magnifications of Av–Au NCs-25 T formed by the reaction of Av–Au NCs and 25 T (A, B, C), and Av–Au NCs-50 T formed by the reaction of Av–Au NCs and 50 T (D, E, F). G Diagram of the interaction between Av–Au NCs and DNA strands with biotin modified at both ends (up: 25 T, down: 50 T)