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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Malting barley carbon dots-mediated oxidative stress promotes insulin resistance in mice via NF-κB pathway and MAPK cascade

Fig. 4

MBCDs induced mice liver oxidative stress. a Volcano plot of differential gene expression. b Cluster map of differential gene expression. c Top 30 GO terms. (n = 3). d The activities of total SOD (T-SOD) and glutathione (GSH) in the serum and the liver. The levels of malondialdehyde (MDA) in the serum and the liver. e, f Oxidative stress-related genes were validated by RT–qPCR. g Protein expression of Nrf2/HO-1 pathway. *p < 0.05 for L vs. C group, #p < 0.05 for H vs. C group, ##p < 0.01 for H vs.C group, ###p < 0.001 for H vs. C group. Results are the mean ± SE (n = 8)

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