Fig. 2
From: Recent advances in smart nanoplatforms for tumor non-interventional embolization therapy
DNA nanorobot for the precise delivery of thrombin. a The design of a thrombin-loaded nanorobot by DNA origami. b, c Tumor accumulation of Cy5.5-labeled nanorobots in MDA-MB-231 mice bearing a human breast tumor at different time points after intravenous injection. d The active targeting effect of the aptamer-conjugated nanorobots on the tumor vascular endothelium. e The detection of the formation of thrombosis in the tumor and thrombosis-induced necrotic tissues was investigated by H&E staining assays. f, g The tumor growth inhibition effect with nanorobot-Th treatment in SK-OV3 and MDA-MB-231 tumors [26]. Copyright©2018, Springer Nature