Fig. 8
From: Recent advances in smart nanoplatforms for tumor non-interventional embolization therapy
Responsively aggregatable sub6 nm nanochelators for tumor vasculature therapy. a The mechanism of Imi-OSi nanochelators in tumor vasculature-targeted therapy. b TEM images of the Imi-OSi nanochelators and the formed aggregates. c The change of the Imi-OSi nanochelator when mixed with PBS, Cu2+ or both PBS and Cu2+. d Representative tumor vessel images indicated that copper deficiency induced thinner tumor capillaries and the formation of blood clots. e The anticancer activity of Imi-OSi nanochelators [60]. Copyright©2019 American Chemical Society