Fig. 5
A, B: T1-weighted MR images of 4T1 tumor-bearing BALB/c mice with or without i.v. injection of Gadavist at 5.0 mg/kg of Gd dosage (A), or ES-MION9 at 5.0 mg/kg Fe dosage (B) under 7.0 T of magnetic field. C, D ΔSNR of the MR images for Gadavist (C), or ES-MION9 (D). E, F Blood clearance profile (E) and in vivo biodistribution of Fe level (F) in the 4T1 tumor-bearing BALB/c mice after i.v. injection of ES-MION9. Fe dosage is 5.0 mg/kg. **P < 0.01